Leukotriene B4 hydroxydehydrogenase



Leukotriene B4 hydroxydehydrogenase (LB4H) is part of the arachidonic acid cycle and is involved in inflammation. The images at the left and at the right correspond to one representative LB4H, i.e. the crystal structure of human Leukotriene B4 hydroxydehydrogenase (1zsv).

3D Structures of Leukotriene B4 hydroxydehydrogenase
1zsv – LB4H - human

2dm6 –gpLB4H/15-oxo-prostaglandin 13-reductase+indomethacin – guinea pig

1v3t, 1v3u - gpLB4H/15-oxo-prostaglandin 13-reductase

1v3v - gpLB4H/15-oxo-prostaglandin 13-reductase+NADP+15-oxo-PGE-2